I Nerazzurri will be stepping out onto the pitch for a European final for the first time since 2010, although Inter enjoyed one of the most memorable nights in their history back then as they won the Champions League with a 2-0 victory over Bayern Munich.
Now, the Italian powerhouses now have the chance to achieve Europa League glory for the first time since the competition was rebranded, and Conte will be desperate to secure Inter's first piece of silverware since 2011.
As is the case with Sevilla, Inter have already secured a route into the Champions League owing to their second-placed league finish, and Conte's side will no doubt feel confident of coming out trumps on Friday having steamrolled their way into the final.
Ahead of the showdown with Sevilla, Sports Mole takes a look at Inter's previous successes and failures in the final of this competition.
Inter Milan 2-1 Roma (agg) (1990-91)
Having bowed out at the semi-final stage to Real Madrid in 1985 and 1986, Inter eventually managed to progress to the final of the UEFA Cup in the 1990-91 campaign, where they would meet fellow Italian giants Roma.
Prior to the 1997-98 campaign, the final would be played over two legs, with Inter welcoming Roma to the San Siro for the first leg in which they enjoyed a comfortable 2-0 victory.
Legendary German midfielder Lothar Matthaus rifled in a penalty to break the deadlock after 55 minutes, and Nicola Berti netted a tap-in not long after to propel Inter into the ascendancy ahead of the second leg.
The two sides could not be separated for the majority of their second-leg clash at the Stadio Olimpico, but Roma gave themselves a glimmer of hope when Ruggiero Rizzitelli gave them the lead with nine minutes to go.
However, a one-goal victory was not enough for Roma as Inter's dominant first-leg display proved decisive in the 1991 tournament, and Giovanni Trapattoni would lift his third and final trophy as Inter's manager before returning to Juventus.
Inter Milan 2-0 Austria Salzburg (agg) (1993-94)
Inter fell at the first hurdle of the defence of their 1991 UEFA Cup triumph, as the holders were knocked out by Portuguese side Boavista in the first round.
Nevertheless, I Nerazzurri found themselves back in the final just two years later, where they would come up against an Austria Salzburg side competing in their first ever European final.
Berti was once again the hero of the hour for Inter in the first leg, as the Italian's 35th-minute strike paved the way for a 1-0 victory in spite of Alessandro Bianchi's red card.
Inter would welcome Salzburg to San Siro for the second leg just a couple of weeks later, and as hard as the Austrian side tried to spoil the party, the staunch rearguard action of I Nerazzurri was simply too strong.
Inter enjoyed a second-leg victory by the same scoreline as the first, as Wim Jonk raced through and scored a delightful chip to secure Inter's second UEFA Cup in the space of four seasons.
However, I Nerazzurri's league campaign was a totally different story that year as the UEFA Cup winners managed to stave off relegation by just one point.
Inter Milan 1-1 Schalke 04 (agg) - Schalke win 4-1 on penalties (1996-97)
Despite their domestic troubles in the 1990s, Inter were enjoying a spate of success in Europe and would have gone into the 1997 final feeling confident of securing a third UEFA Cup triumph.
With all-time great Javier Zanetti finding his feet in the Nerazzurri side by this point, Inter travelled to Schalke for the first leg, with the German side featuring in the final for the first time in the club's history.
However, Inter ultimately came out on the wrong end of the scoreline at the Parkstadion, as Marc Wilmots powered home from 30 yards to give Schalke the upper hand in the 1997 final.
Returning to familiar surroundings for game number two, the 80,000-strong crowd at San Siro did all they could to spur their side on and hope for an improved performance at the same time.
No more goals were to be had in extra-time and the last-ever two-legged final would ultimately be decided by a penalty shootout, and Zamorano soon went from hero to villian as his spot-kick was saved by Jens Lehmann.
Aron Winter then sent his penalty wide of the mark for Inter, and Schalke scored four out of four to condemn Hodgson's side to European heartbreak in front of their own fans.
Inter Milan 3-0 Lazio (1997-98)
Just one year on from their disappointment against Schalke, a new-look Inter - led by Luigi Simoni - would face off against Italian counterparts Lazio at the Parc des Princes.
The tournament's first-ever one-legged final was soon to be graced by the elegance and flair of Ronaldo, but not before Inter had already put the tie to bed by the hour mark.
Zamorano kept up his goalscoring feats in the competition by lashing in a half-volley within five minutes of the opening whistle, and Zanetti got in on the act in the second half with a thunderous effort from outside the area.
The spectacular goals did not stop there for I Nerazzurri. Ronaldo showed the world exactly what he was capable of as he wrong-footed Lazio goalkeeper Luca Marchegiani before calmly slotting home for Inter's third.
Inter's Taribo West and Lazio's Matias Almeyda both received their marching orders late on, but Inter eventually secured their third UEFA Cup crown with relative ease in Simoni's only season in charge.