Neilson's side head to Glasgow on the opening day, and will face local rivals Hibernian a week later, in what many claim will be the toughest Scottish Championship in recent history.
However, the 33-year-old claims that he is not daunted by the prospect.
He is quoted as saying in the Daily Record: "It's still great. The players will be desperate to be involved so they will have to work hard in pre-season.
"It's a fantastic introduction to Scottish football for the new guys and what a start to their Hearts careers with two full houses to play in front of.
"They are high-quality matches which give us the chance to lay down a marker for the season."
Neilson, who played for Hearts for 10 years, was appointed as manager in May.