Both teams will be looking to get back to winning ways in this one having failed to come away with all three points last time out.
Guangzhou City's downward spiral continued in Monday's meeting against Zhejiang Professional as they suffered a fifth straight defeat.
Jean-Paul van Gastel's men conceded four unanswered goals inside the opening 50 minutes to Jin Cheng, Donovan Ewolo and Franko Andrijasevic before Gong Zhang and Tixiang Li halved the deficit with two late strikes.
With no points picked up from their five outings this term, the Blue Lions remain rooted to the bottom of the standings but can count themselves lucky to be only three points adrift of safety at the moment.
Next up is the challenge of an opposing side who came out on top in each of the last three clashes between the teams by an aggregate score of 8-2.
Having lost three straight home games prior to Friday's encounter, the hosts will be aiming to arrest their slump in form and get their season up and running.
Changchun Yatai had to make do with a point for the third time in four matches following a goalless draw against Henan Songshan Longmen at the Development Area Stadium on Monday.
In what was a fairly even contest, Chen Yang's men failed to find the breakthrough despite having just about the better chances on the day.
Nonetheless, the Jilin-based outfit have moved up to 10th place in the league table, albeit now a whopping seven points shy of current leaders Wuhan Three Towns and Shanghai Shenhua.
Still yet to win on the road since the turn of the year, Friday's visitors set out to heap more misery on their hosts and secure a much-needed three points.
Twenty-year-old Zhuoxuan Li will be pushing to reclaim his place in the starting XI after he was dropped to the bench in Guangzhou's last outing against Zhejiang.
Despite failing to find the back of the net in the aforementioned game, Hong Gui racked up his second assist of the season and has now been directly involved in two-thirds of his side's total goals this term.
Tan Long will be looking to deliver the goods for Changchun once again having grabbed a game-winning hat-trick in the last edition of this fixture.
However, the Chinese forward has had little luck in front of goal ever since and now would be as good a time as any to get back on the scoresheet.
Guangzhou City possible starting lineup:
Cheng; Fu, Yi, Jiang; Huang, Zhang, Wang, Zhang; Chen, Gui, Li
Changchun Yatai possible starting lineup:
Wu; Sun, Okore, Han; Liao, Tudi, Zhang, Rao; Tan, Negao, Erik
We say: Guangzhou City 0-2 Changchun Yatai
Guangzhou have been abysmal at both ends of the pitch and it is hard to see them coming away from this one with anything. We are backing the visitors to claim all three points via a routine victory come the full-time whistle.
For data analysis of the most likely results, scorelines and more for this match please click here.