Abelardo Fernandez's side recorded a 2-0 victory over Alaves on their return to action on Saturday, but Champions League hopefuls Getafe suffered a disappointing 2-1 defeat at Granada.
Getafe have enjoyed an impressive 2019-20 campaign to date, picking up 46 points from their 28 matches to occupy fifth position in the table.
The capital club suffered a 2-1 loss at Granada on Friday night, though, and could be three points off the top four by the time that Sunday's fixtures have taken place.
Getafe are currently fifth - level on points with fourth-placed Sociedad and a point ahead of sixth-placed Atletico Madrid - but both Sociedad and Atletico are in action on Sunday, and it would not be a surprise to see Jose Bordalas's side enter this match in sixth spot.
The Madrid-based outfit only just missed out on the top four last season as they finished fifth but another impressive campaign to date has left them in the argument for a Champions League spot at this stage.
The Catalan outfit are still bottom of the table but are now level on points with 19th-placed Leganes and just two points behind 18th-placed Mallorca. Celta Vigo in 17th, meanwhile, are just three points ahead of Espanyol.
The White and Blues have not played outside of Spain's top flight since the 1993-94 campaign, while they finished seventh in La Liga last term, picking up an impressive 53 points in the process.
It would be a huge surprise if they were relegated this season but 15 defeats and just five wins from 28 matches is an indication of their troubles throughout the 2019-20 campaign.
Espanyol have not beaten Getafe in the league since November 2017, meanwhile, and suffered a 3-0 defeat when they last travelled to the capital side in December 2018.
Getafe La Liga form: WLLWDL
Getafe form (all competitions): WLLWDL
Espanyol La Liga form: WDLDLW
Espanyol form (all competitions): LLWDLW
Mata should join Jorge Molina in the final third, while Maksimovic and Arambarri are expected to feature in midfield as Bordalas prepares to shuffle his pack from the defeat at Granada.
The Catalan outfit's squad is in good shape heading into the contest, and it would not be a surprise to see the bulk of the XI that started against Alaves take to the field here.
Getafe possible starting lineup:
Soria; Suarez, Dakonam, Cabaco, Nyom; Etebo, Arambarri, Maksimovic, Cucurella; Mata, Molina
Espanyol possible starting lineup:
Diego Lopez; J Lopez, Espinosa, Cabrera, Vila; Melendo, David Lopez, Roca, Embarba; Calleri, Wu Lei
We say: Getafe 2-1 Espanyol
Espanyol picked up a strong result against Alaves on their return to action, but Getafe will be much stronger than against Granada due to the return of three key players. We are expecting a tight match in the Spanish capital but fancy the home side to have enough to pick up all three points to boost their top-four challenge.