The World Cup winners get their campaign underway on Sunday evening when they entertain the Scots at Signal Iduna Park.
Despite his side being favourites to win the match tomorrow night, Low is confident that Scotland will put up a dogged fight.
"They have quality players and have nothing to lose in this match so will play with no fear. We know all about their team and their biggest strength is that they are a team," he is quoted as saying by Goal.com.
"They have won twice against Croatia and drew against the USA and Nigeria and so we know they are a very good team. It will be a difficult match for us."
Germany reached the semi-finals of the 2012 European Championship before losing to Italy.