Lyon vs. Sparta Prague (Thursday, 5.45pm)
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Two weeks on from their dramatic seven-goal thriller, Lyon and Sparta Prague meet again on Thursday evening in Europa League action at the Groupama Stadium.
It was the French side who prevailed last time to stay top of Group A, but Sparta will be determined to get revenge.
We say: Lyon 2-1 Sparta Prague
Lyon still have room for improvement this campaign but they have been excellent in Europe so far and have the benefit of home advantage here. We think that should be enough for them to secure another three points to maintain their 100% record and cement their place at the top of the group.
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Brondby vs. Rangers (Thursday, 5.45pm)
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Rangers travel to Denmark to take on Brondby on Thursday evening in the fourth round of Europa League group games.
The hosts will be looking for revenge after losing away at Ibrox two weeks ago, but their opponents also need a win to lift them into the top two of Group A.
We say: Brondby 1-2 Rangers
Both sides are attack-minded and are in need of a victory from this game, which should provide goals and plenty of entertainment. We think the visitors should have enough class to edge out their opponents and grab a crucial away victory.
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Real Sociedad vs. Sturm Graz (Thursday, 5.45pm)
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Real Sociedad play host to Sturm Graz on Thursday evening knowing that victory will move them closer to securing a place in the Europa League last 32.
Meanwhile, Graz make the trip to the Anoeta Stadium having suffered three successive defeats in Group B, leaving the visitors requiring a surprise win against the La Liga side.
We say: Real Sociedad 2-0 Sturm Graz
While Sociedad have not scored goals freely all season, it has not stopped them being difficult to beat. With that in mind, we are predicting a comfortable win for the home side, potentially with a strike coming in either half.
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Monaco vs. PSV (Thursday, 5.45pm)
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Monaco play host to PSV Eindhoven on Thursday evening knowing that victory may be enough to book their place in the last 32 of the Europa League.
However, PSV can move to the top of Group B with all three points, and the result of this contest could prove pivotal come the end of the group stages.
We say: Monaco 1-1 PSV Eindhoven
Both teams will be confident of collecting a result on Thursday, a scenario which should make this an entertaining tussle. Nevertheless, we are not expecting many goals, leading us to predict a low-scoring draw.
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Legia vs. Napoli (Thursday, 5.45pm)
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Serie A leaders Napoli continue their Europa League campaign on Thursday evening, as they look to seal a double over Group C rivals Legia Warsaw at Stadion Wojska Polskiego.
After a late breakthrough helped the Italian club to dispatch the Polish champions on home soil, another win would take them above their ailing opponents to the top of the standings.
We say: Legia Warsaw 1-2 Napoli
Napoli can re-establish themselves as favourites to progress, after a sluggish start put them in some trouble before back-to-back games with Legia.
While their margin of victory may not be as wide as many expect - as they could take their foot off the gas if they secure a first-half lead - the visitors are riding the crest of a wave and will not be stopped by a stumbling home side.
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Olympiacos vs. Frankfurt (Thursday, 5.45pm)
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It is a battle of first vs. second on Thursday as the two top teams of Group D compete against each other in the latest Europa League fixture.
Eintracht Frankfurt will travel to Greece to face Olympiacos, with just one point separating them both in the table.
We say: Olympiacos 2-2 Eintracht Frankfurt
Both teams will want to cement themselves at the top of Group D on Thursday, and with Frankfurt having the chance to qualify for the next phase of the competition with a win, there is plenty riding on this match.
However, each club have proven their qualities throughout the season, but it is the hosts who are in stronger form when it comes to league matches, and it could see the two end up battling to a draw.
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Galatasaray vs. Lokomotiv (Thursday, 5.45pm)
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Galatasaray will aim to cement their position at the top of Europa League Group E when they welcome Lokomotiv Moscow to Turkey for Thursday's battle.
A Kerem Akturkoglu winner saw the Super Lig side prevail 1-0 during their matchday three clash with Lokomotiv, who are rooted to the bottom of the standings.
We say: Galatasaray 2-1 Lokomotiv Moscow
Galatasaray's rock-solid rearguard has served them well in European competition so far, but Lokomotiv appear to be experiencing a much-needed case of new manager bounce under Gisdol.
However, the visitors' lengthy absentee list is set to harm them once again, and we expect Terim's side to all but guarantee their spot in the knockout rounds with a third win from four here.
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Genk vs. West Ham (Thursday, 5.45pm)
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West Ham United's European journey continues on Thursday when they travel to face Genk where they shall be aiming to maintain their unbeaten start to Group H.
On the other hand, the hosts currently sit bottom after consecutive defeats, but a victory in midweek could take them into the top two.
We say: Genk 0-2 West Ham United
Genk might have the home advantage in this game, but it is West Ham United with all of the confidence and momentum behind them which should prove to be enough to secure the victory.
The Hammers are yet to concede a goal in the tournament and that record could also end up continuing here, with the Premier League outfit putting in some brilliant performances as of late.
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Leicester vs. Spartak Moscow (Thursday, 8.00pm)
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After a spectacular first encounter in Russia last month, Leicester City and Europa League rivals Spartak Moscow reconvene at the King Power Stadium on Thursday.
With the sides split by just a point in the finely-poised Group C standings - the Foxes hold that slim advantage - another entertaining affair could be in store between the bottom two in the table.
We say: Leicester City 3-1 Spartak Moscow
As this group reaches the stage where points become crucial, a win for Leicester could put them within touching distance of the last 16, while Spartak would almost certainly see their chances ended with a defeat.
That is the likeliest outcome on Thursday evening, as the Foxes' forward options can make mincemeat of the Muscovites if anywhere near top form.
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Antwerp vs. Fenerbahce (Thursday, 8.00pm)
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The bottom two teams of Group D will collide on Thursday in the latest Europa League fixture, as Royal Antwerp host Fenerbahce, with each team needing a victory.
Neither club have managed to pick up a win in the competition during the opening three games, which includes a draw against each other the last time they met.
We say: Royal Antwerp 1-2 Fenerbahce
This is a fixture between two teams in poor form who are struggling for confidence at the moment, both in Europe and their respective leagues.
However, Fenerbahce should have enough quality and experience to see them through in what will no doubt be a tightly-fought encounter.
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Braga vs. Ludogorets (Thursday, 8.00pm)
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Ludogorets Razgrad are on the verge of equalling an unwanted record in the Europa League as they prepare for Thursday evening's trip to Group F rivals Braga.
The Bulgarian side have gone 15 games without a win in the competition, one short of the record held by Rosberg, and must end that run if they are to have any hope of advancing.
We say: Braga 1-0 Ludogorets Razgrad
Ludogorets need a victory to have any chance of remaining in the Europa League, whereas Braga are looking to keep the pressure on Group F leaders Red Star.
The visitors could equal an unwanted competition record if they fail to win which, given their opponents' recent form, we can see being the case here.
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Red Star vs. Midtjylland (Thursday, 8.00pm)
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Red Star Belgrade will be looking to tighten their hold on top spot in Europa League Group F when they welcome FC Midtjylland to Rajko Mitic Stadium on Thursday evening.
The Serbian heavyweights have won two and drawn one of their opening three games and are a point clear at the summit, while Midtjylland are five points worse off in third.
We say: Red Star Belgrade 2-0 FC Midtjylland
Midtjylland have an underwhelming record in Europe, particularly away from home, whereas Red Star do not tend to lose on their own patch.
The hosts will be motivated to strengthen their status as Group F leaders and we can see them comfortably doing so here, avenging the 1-1 draw from two weeks ago in the process.
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Marseille vs. Lazio (Thursday, 8.00pm)
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Marseille and Lazio will aim to make this week's Europa League contest a better watch for the neutrals when they reconvene at the Orange Velodrome for Thursday's Group E contest.
The two continental giants played out a drab goalless stalemate on matchday three and are separated by one point in the rankings at the midway point.
We say: Marseille 1-1 Lazio
With only three goals scored and two conceded between them in the Europa League between them so far, sparks may not fly at the Orange Velodrome, but both managers will be desperate for their sides to consign their drab matchday three affair to history.
Marseille's new-found defensive resilience and home advantage will work in their favour, but we still expect an inconsistent Lazio to do enough to come away with a point as their winless streak on the road continues.
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B. Leverkusen vs. Real Betis (Thursday, 8.00pm)
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Bayer Leverkusen and Real Betis meet again on Thursday evening, two weeks after their last Europa League encounter - this time at the BayArena.
The teams could not be separated a fortnight ago, playing out a 1-1 draw, and remain level on seven points at the top of Group G.
We say: Bayer Leverkusen 1-1 Real Betis
Both teams will likely be more worried about losing than winning, which could lead to a cagey affair. The hosts have home advantage but are in terrible form and would likely take a draw in this one, so we're backing a final score of 1-1.
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Ferencvaros vs. Celtic (Thursday, 8.00pm)
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The bottom two sides in Group G meet as Celtic travel to Hungary to take on Ferencvaros at the Groupama Arena in Thursday evening's Europa League action.
The Scottish giants finally got off the mark in their previous meeting with the group underdogs a fortnight ago but can be sure that their opponents will be out for revenge on home soil.
We say: Ferencvaros 2-3 Celtic
Both sides are in desperate need of a win here so will likely be going all out. Despite a more conservative shape for the Hungarians, this could well see a few goals and we fancy Celtic to get more of them than their opponents and claim the all-important three points.
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Dinamo Zagreb vs. Rapid Vienna (Thursday, 8.00pm)
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Europa League action continues this Thursday as Dinamo Zagreb host Rapid Vienna in the latest Group H contest, with both teams having three points to their name.
The visitors were able to defeat their opponents last time they met, but each club shall be hoping to place some pressure on current leaders West Ham United.
We say: Dinamo Zagreb 1-1 Rapid Vienna
Both teams head into this fixture with plenty of confidence, having picked up great results in their respective leagues.
With each club needing three points in this fixture, this could easily end up being a case of two teams cancelling each other out as they push for the victory.