Fernando Santos's side are currently top of League A Group 3 on goal difference, picking up six points from their two games in the section against Croatia and Sweden.
The Nations League holders were also in action in an international friendly on Wednesday night, playing out a goalless draw with Spain in Lisbon.
Here, Sports Mole looks at how Portugal could line up against Didier Deschamps's team.
A 4-3-3 formation is expected to see Felix and Bernardo Silva join Cristiano Ronaldo in attack, while Manchester United's Fernandes is likely to feature alongside Danilo Pereira and William Carvalho in midfield.
The back four is also not expected to include any surprises, with new Manchester City centre-back Dias likely to be joined by the experienced Pepe, while Joao Cancelo should edge out Nelson Semedo at right-back, with Raphael Guerreiro lining up in the opposite side.