Huddersfield will be looking to make it back-to-back wins after an impressive display away to Swansea City.
In a game that lacked moments of inspiration, Derby fell short in many departments and were not able to emulate the flowing football that has come to be expected from this Derby side.
To add to Cocu's concerns, the Rams now face a string of tough fixtures, which include a rejuvenated Nottingham Forest side under Chris Hughton and a strong Bournemouth outfit.
In a week where Huddersfield fans will have been more worried about their club's financial situation than form on the pitch, the win at Swansea will have been a welcome distraction.
The club have seen many players leave for handsome fees in the transfer window, and when a deal for Rolando Aarons fell through last week, fans were left understandably frustrated.
All being said, Danny Cowley will have enjoyed the character shown by his team to come from behind to win and will be looking to take that momentum into this midweek fixture.
Unbeaten in their last three, Huddersfield will be looking to make the most of their home advantage to make it three wins in four, helping them climb into the top half of the table.
Huddersfield Town Championship form: LLWDW
Huddersfield Town form (all competitions): LLLWDW
Derby County Championship form: LWLLL
Derby County form (all competitions): LWLLLL
Cocu may choose to select Tom Lawrence after he was able to come through a substitute appearance against Watford unscathed.
Wayne Rooney will undergo an urgent COVID-19 test after he visited an unknowingly infected friend.
Huddersfield Town possible starting lineup:
Hamer; Pipa, Stearman, Sarr, Toffolo; Eiting, Hogg; Mbenza, O'Brien, Koroma; Campbell
Derby County possible starting lineup:
Marshall; Byrne, Clarke, Davies, Buchanan; Rooney, Bird; Knight, Lawrence, Jozwiak; Marriott
We say: Huddersfield Town 1-0 Derby County
Having started to string results together, Town look the more convincing of the two teams at present. We expect a close game, but in a fixture where Derby could be without captain Wayne Rooney, we see Huddersfield shading it to seal their second home win of the season.