Their 5-0 victory over bitter rivals Nottingham Forest will live long in the memory, but it remains their only success in their last six matches - a run that has seen their automatic promotion hopes go up in smoke.
They still sit comfortably in the playoff positions with nine points separating them from seventh-placed Forest, but McClaren will be fully aware that they cannot afford to hit a bad run of form at this stage of the season.
The Rams remain the second highest scorers in the league, but that golden touch in front of goal has deserted them lately, with the notable exception of the win over Forest.
Things are better at home, however, where they have lost just twice in the league since September, a run that stretches 15 games. They have also kept things tight at the back in recent weeks, conceding just one goal in their last five home league outings.
For Charlton, it is the second trip to the East Midlands in the space of a week having picked up a priceless 1-0 victory over Forest on Tuesday to keep themselves clear of the relegation zone.
Three points is still the gap between themselves and the bottom three, although the Addicks' destiny is very much under their own control considering that they have three games in hand over the majority of their relegation rivals.
Of course, they need to make the most of those games in order for them to mean anything, but new manager Jose Riga has made a promising start to life at The Valley with just one defeat in five matches so far.
Goals are still very much an issue for Charlton, who have scored a league-low 26 in their 35 games so far this season and have managed just two in their last seven in all competitions.
However, Riga has certainly improved things at the other end of the pitch with four clean sheets in his five games at the helm so far.
There are even signs of improvement on the road, with Tuesday's victory over Forest ending a 10-match winless streak away from home for the Addicks.
Possible starting lineups
Derby: Grant; Wisdom, Keogh, Buxton, Forsyth; Hughes, Hendrick, Bryson; Bamford, Martin, Russell
Charlton: Hamer; Wilson, Morrison, Dervite, Wiggins; Ajdarevic, Jackson, Poyet, Cousins, Ghoochanneijhad; Obika
Sports Mole says: 1-0