The Eagles are currently 17th in the division, and the former Stoke City manager said that his current side must view every remaining league game as imperative to their safety.
"Every game in the Premier League is enormous, there's 14 cup finals left," he told reporters.
"We've got to treat every one like a cup final. There's so many teams involved; there's going to be a lot of twists and turns.
"The crucial thing is to get one point more than the team that finishes third from bottom."
Palace host West Bromwich Albion on Saturday.