Find out how all of the action unfolded on the South coast courtesy of Sports Mole's minute-by-minute updates below.
SOUTHAMPTON SUBSTITUTES: Gunn, Vestergaard, Davis, Romeu, Targett, Long, Austin
CHELSEA SUBSTITUTES: Caballero, Fabregas, Pedro, Kovacic, Zappacosta, Cahill, Morata
Fulham had been tipped to finish in the top 10, but Slavisa Jokanovic's side are only 17th and with a -12 goal difference. They desperately need a win after the international break.
SOUTHAMPTON XI: McCarthy; Yoshida, Bednarek, Hoedt; Soares, Hojbjerg, Lemina, Bertrand; Redmond, Gabbiadini, Ings
CHELSEA XI: Arrizabalaga; Azpilicueta, Rudiger, Luiz, Alonso; Kante, Jorginho, Barkley; Willian, Giroud, Hazard
If you would like to read our on-the-whistle match report, you can do so by clicking here. Goodbye for now.