The Blues travel to their London rivals tonight in the fourth round of the competition.
Following a tough win over Manchester City in the Premier League at the weekend, Schurrle admits that he would not be surprised if there were a number of alterations to Chelsea's starting XI.
"I think the manager will change many positions but we have high quality in every member of the squad and there will be no problem for us," he told the club's official website.
"I think Arsenal will change their players, too, and it's going to be a good match.
"I am very happy to be a part of our squad, and with a team like Chelsea you want to win every competition you are in, so we'll do everything to win the match."
Chelsea have won the tournament four times, with their last success coming under Mourinho in 2007.