Group H's top two clash in London this Tuesday, as Chelsea and unbeaten leaders Juventus battle it out for supremacy in their Champions League section.
While the Old Lady triumphed in Turin when the clubs last met - before going on to seal progress to the last 16 with four wins from four - the reigning champions are just a point away from confirming their place in the knockout stages.
Match preview
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After maintaining their three-point lead at the top of the Premier League table with a routine win at Leicester City on Saturday, in-form Chelsea will shift their focus to prolonging their defence of the Champions League trophy they lifted for the second time last May.
Sitting second in the group behind this week's opponents, their only defeat so far came in a close-fought encounter at the Allianz Stadium back in September, as a 1-0 Juventus win was secured by Federico Chiesa's goal at the start of the second half.
Those were the only points dropped by the Blues to date, after an opening win at home to Zenit was followed by dominant victories against Malmo on each of the last two matchdays. Though Thomas Tuchel's men only prevailed by a single goal in Sweden last time out, they assumed complete control once again, and won the two games by a 5-0 aggregate scoreline.
The Blues' league form since first disposing of the Allsvenskan champions will give Tuesday's visitors serious cause for concern too, as they strode to a 7-0 victory over Norwich City and put three past both Newcastle and Leicester. Those goals have been coming from all quarters of a confident side, as Chelsea's 30 Premier League strikes this term have been scored by 15 different players.
Tuchel ensures they keep things tight at the back as well, with the capital club having kept six clean sheets in their last eight matches. Not only that, but they are also yet to concede more than once in any game during the 2021-22 campaign.
Such defensive solidity - and a forbiddingly deep squad - means that they will be one of the teams to avoid in the draw for the last 16, should they confirm their place in the coming weeks. With fixtures piling up between here and Christmas, their head coach will want to do so at the first possible opportunity.
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In stark contrast to their patchy domestic form, Juventus sit atop Group H with maximum points so far, after they sealed a double over Zenit St Petersburg earlier this month.
Having won their first three fixtures without conceding a goal, the Bianconeri finally succumbed to a Leonardo Bonucci own goal in Turin, but were still able to run out 4-2 winners over the Russian champions. As a result, Juventus will be confirmed in first place if they avoid defeat against Chelsea this week, following improved fortunes in Serie A.
Since his much-heralded return in the summer, Max Allegri has seen his side stumble to defeats against several mid-table teams, such as Sassuolo and Verona, but back-to-back wins either side of the international break have lifted them to seventh in the standings - still well off the Scudetto pace.
Juve ended a three-game winless run in the league with a home victory against 10-man Fiorentina at the start of November - marking Allegri's 200th win as the club's head coach - and they followed that up with a gritty 2-0 success against Lazio in Rome, when a penalty in each half from stand-in skipper Bonucci secured the points.
As they return to continental action, Juventus can boast a remarkable record of 14 wins from their last 15 group games. For that reason, they will bring some hard-earned confidence to English soil, where they remain unbeaten in five matches since a notorious 4-1 loss at Chelsea's west London rivals Fulham in the 2010 Europa League.
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Team News
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Having been without both of his main strikers following injuries suffered on Champions League duty, Thomas Tuchel has been able to welcome back both Romelu Lukaku (ankle) and Timo Werner (thigh) to training in recent days.
While Werner was an unused substitute at Leicester on Saturday and could now start, Lukaku is only set to feature on the bench, as he maps out a cautious return to first-team action.
Several times a champion in this competition, Mateo Kovacic has been out since suffering a hamstring injury in training late last month, while wing-back Marcos Alonso only returned from an ankle injury at the weekend. The latter may be involved though; pressing Ben Chilwell for his place on the left.
Mason Mount missed England's recent internationals after undergoing dental surgery but started in the Premier League and is expected to play in support of either Kai Havertz - who hopes to overcome a hamstring problem - or Werner up front.
Juventus, meanwhile, aim to have Paulo Dybala at their disposal for the trip to London, and the diminutive striker remains hopeful of being involved at some stage.
His condition will be monitored regularly before the match, but Welsh midfielder Aaron Ramsey is sidelined again and captain Giorgio Chiellini's presence is once more in doubt due to an Achilles problem.
Max Allegri also has concerns about Federico Bernardeschi, who was injured representing Italy, but Moise Kean is available and could feature up front should Dybala miss out. Scorer of the winner in the reverse fixture, Federico Chiesa is a more likely option to join Alvaro Morata in attack for the Bianconeri.
Chelsea possible starting lineup:
Mendy; Rudiger, Christensen, Silva; James, Jorginho, Kante, Alonso; Pulisic, Mount; Havertz
Juventus possible starting lineup:
Szczesny; Danilo, Bonucci, De Ligt, Sandro; Cuadrado, McKennie, Locatelli, Rabiot; Morata, Chiesa
We say: Chelsea 1-0 Juventus
Chelsea can gain a measure of revenge for their defeat in Italy earlier this season by ending Juve's flawless record and ensuring the race for top spot goes down to the final matchday in Group H.
Though the visitors can be flaky against some of the more modest sides they encounter, they rarely concede many in big games, so will be edged out by the odd goal at Stamford Bridge due to their hosts' wealth of attacking options.
Top tip
Jonathan O'Shea
Data Analysis
Our analysis of all available data, including recent performances and player stats up until an hour before kickoff, suggested the most likely outcome of this match was a Chelsea win with a probability of 37.29%. A win for Juventus had a probability of 36.49% and a draw had a probability of 26.2%.
The most likely scoreline for a Chelsea win was 1-0 with a probability of 9.55%. The next most likely scorelines for that outcome were 2-1 (8.25%) and 2-0 (6.32%). The likeliest Juventus win was 0-1 (9.43%), while for a drawn scoreline it was 1-1 (12.46%). The actual scoreline of 4-0 was predicted with a 0.9% likelihood. Our team at Sports Mole and our data analysis both correctly predicted that Chelsea would win this match.
