The Royals have picked up maximum points from their first two matches to top the pile, while Cardiff have made a mixed start to the campaign with three points from six.
Not a great deal was expected of Reading this season, with even supporters questioning the appointment of relative unknown head coach Veljko Paunovic.
However, the former Chicago Fire boss has made a perfect start to his Royals tenure - in the league, at least - thanks to 2-0 wins over Derby County and Barnsley.
Paunovic is now looking to become the first non-British manager to win his first three Championship matches in charge since Marcelo Bielsa did so for Leeds in August 2018.
The Berkshire outfit do not tend to come away from Cardiff with maximum points, though, winning just one of their last nine away league meetings with the Bluebirds.
Cardiff are aiming to string together back-to-back wins after easing to a 2-0 victory at Nottingham Forest last weekend through Kieffer Moore's first-half double.
That came on the back of disappointing 3-0 and 2-0 defeats to Northampton Town and Sheffield Wednesday respectively in the first set of fixtures in the EFL Cup and Championship.
Neil Harris will certainly hope that a corner has been turned with that win at the City Ground, with Moore going a long way to showing why he was such a bargain buy at just £2m.
City may have lost comfortably to Wednesday in their opening league game, but they have lost their opening two home matches of a season twice in the last 21 years.
It is far too early in the campaign to label this a pivotal game for City, though the mood around the club could alter drastically depending on the outcome of Saturday's result.
Cardiff City Championship form: LW
Cardiff City form (all competitions): LLW
Reading Championship form: WW
Reading form (all competitions): WWLW
Meite marked his return from suspension with a goal against Barnsley last weekend and should come back into the starting lineup for this trip to the Welsh capital.
Paunovic made his first signing as Royals boss on Wednesday with the arrival of Lewis Gibson on loan from Everton, but this game may come too soon for him to make his debut.
As for Cardiff, the fitness of star man Lee Tomlin remains a big worry for Harris - the playmaker has not been able to start any of Cardiff's three matches so far this season.
That is likely to be the case here, even if he did get some minutes under his belt for the Under-23s side in the week, while left-back Joe Bennett hobbled off last weekend.
Harris has the option to rotate things slightly in midfield and attack, though it may well be a case of sticking with a winning formula should Bennett be fit.
Cardiff City possible starting lineup:
Smithies; Osei-Tutu, Morrison, Nelson, Bennett; Bacuna, Ralls, Pack; Ojo, Moore, Hoilett
Reading possible starting lineup:
Cabral; Araruna, Morrison, Moore, Richards; Rinomhota, Laurent; Olise, Swift, Ejaria; Joao
We say: Cardiff City 1-1 Reading
Reading have made an impressive start to their campaign by winning three games out of four in all competitions. Cardiff looked a lot better in their most recent outing and are expected to challenge for promotion this term, but they are winless in nine against the Royals and may have to settle for a point this weekend.