Tim Krul drops to the bench to be replaced in goal by Mathew Ryan, while further forward there are starts for Glenn Murray and Jose Izquierdo as the hosts go in search of a fourth home league victory on the trot.
Anthony Knockaert, meanwhile, serves the second of his three-match suspension.
For the Foxes, Claude Puel makes just the one change from the loss to Chelsea last time out as Shinji Okazaki falls in behind Jamie Vardy as Kelechi Iheanacho - who broke his hand on Nigeria duty - drops to the bench.
Brighton & Hove Albion: Ryan; Schelotto, Dunk, Duffy, Bong; Kayal, Gross, Propper, Locadia, Izquierdo; Murray
Subs: Krul, Suttner, Bruno, Hemed, Goldson, March, Baldock
Leicester City: Schmeichel; Simpson, Maguire, Morgan, Chilwell; Mahrez, Ndidi, Iborra, Albrighton; Okazaki; Vardy
Subs: Jakupovic, Gray, Iheanacho, Silva, Dragovic, Fuchs, Diabate
Follow all the action from this afternoon's match with Sports Mole's live commentary here.