Middlesbrough, on the other hand, are just seven points clear of the relegation zone, although a win on Saturday could see them climb as high as 14th.
Brentford's run of six consecutive home league wins came to an end in their last match at Griffin Park, with the West London club losing 1-0 to promotion rivals Nottingham Forest.
That defeat was just the Bees' third defeat on their home patch all season and their first since they lost to Huddersfield Town back in November.
However, a 5-1 win away to Hull City in their most recent game put their promotion hopes back on track and they are now just six points adrift of leaders West Bromwich Albion.
With two points separating Bristol City in sixth and Fulham in third, the playoffs battle is heating up and Thomas Frank's side know they cannot afford another slip up.
Middlesbrough's mini revival has come to a bit of a standstill in recent weeks, with the North-East club picking up just three points from their last four games.
A run of four consecutive wins around the new year moved them away from immediate danger, but manager Jonathan Woodgate will be aware that they can be pulled back into a relegation scrap if they fail to pick up points soon.
Boro's form away from the Riverside has been poor all season, with the club managing just two Championship wins, although they did come against West Brom and Preston North End.
A win on Saturday would be just their ninth league victory of the season, but with a few key players closing in on a return their chances against Brentford look to have been boosted.
Brentford Championship form: LWWDLW
Brentford form (all competitions): WWDLLW
Middlesbrough Championship form: WWDLDD
Middlesbrough form (all competitions): DDLLDD
Brentford's hat-trick hero from the 5-1 win at Hull Said Benrahma is a doubt for Saturday's match due to personal reasons, in a blow to the Bees hopes.
Pontus Jansson, Nikos Karelis, Josh Clarke, Mathias Jensen, Ellery Balcombe and Kamo Mokotjo are all out, while Sergi Canos could be set for a return to first team action following a knee injury he picked up in October.
Brentford possible starting lineup:
Raya; Dalsgaard, Jeanvier, Pinnock, Henry; Dasilva, Norgaard, Marcondes; Mbuemo, Watkins, Castillo
Middlesbrough possible starting lineup:
Pears; Spence, McNair, Fry, Friend; Wing, Howson, Saville; Nmecha, Fletcher, Tavernier
We say: Brentford 2-1 Middlesbrough
Brentford have been an exciting side to watch all season and while their home run has now come to an end, they are still favourites for this match. The potential absence of Benrahma is a blow, but Boro are still unlikely to have enough to hold off their formidable attack.
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