The two sides meet at Villa Park on Tuesday with the three points vital to both team's chances of securing their Premier League status for another season.
Wanderers are currently six points behind their hosts in the Premier League table, but Reo-Coker believes that his former club will be feeling the pressure.
"I'll tell you now, there will be more pressure on Aston Villa than there is on us," he told BBC Radio Manchester. "Villa are in the mix. It makes it better for us that Villa will be there and will be on the edge.
"It gives us the advantage to go there and get the result, but we have to take advantage of that. No more slack performances.
"It's about Bolton Wanderers and it's about us getting a result. That's all that matters. It's a great opportunity for us."
The 27-year-old joined Bolton from Villa last summer.