Famalicao vs. Santa Clara (Friday, 7.00pm)
Ivo Vieira's side face the Azoreans, who have won just one of their last seven top-flight matches, conceding 10 goals in the process.
We say: Famalicao 1-1 Santa Clara
Santa Clara have little to play for as they head down the home straight, while Famalicao are still in danger of relegation and securing three points would provide a massive boost in their bid to avoid the drop.
However, with little to separate the two teams, a score draw could be on the cards at the Municipal Stadium Famalicao.
Boavista vs. Tondela (Friday, 9.15pm)
This encounter at the Estadio do Bessa could be a feisty affair, as the Panthers have had a player dismissed in five of their last eight league matches, while a player has been sent off in two of Tondela's previous four games.
We say: Boavista 2-2 Tondela
Securing all three points on Friday is crucial for Boavista in their quest to survive, while a win for Tondela could help them cement a top-half finish.
Both sides have struggled defensively in recent weeks and with little to separate the two teams, an entertaining score draw could be on the cards at the Estadio do Bessa.