Maritimo vs. Farense (Saturday, 3.00pm)
The hosts currently sit at the foot of the table, while Farense sit just one point ahead in the relegation playoff place, although either side can move out of the bottom three with a victory on Saturday.
We say: Maritimo 1-1 SC Farense
In what is one of the biggest games at the bottom of the Primeira Liga this season, Saturday's game could definitely go either way as both sides will be desperate for a victory over their rivals in the battle for survival.
On this occasion, we cannot quite separate the sides and are predicting a draw due to each team being slightly too fearful of a defeat to fully commit to attacking - a result which does not particularly benefit either outfit.
Boavista vs. Rio Ave (Saturday, 3.30pm)
The hosts picked up a win over Belenenses last Sunday to move up to 15th spot, while Rio Ave's winless run was extended to three games as they suffered a 2-0 defeat to Gil Vicente.
We say: Boavista 2-0 Rio Ave
We see the hosts digging deep to pick up another impressive result on Saturday, as they look to move further away from the drop zone.
Given the situations of the two sides, Boavista have far more to play for, and that extra desire could drive them to what would be another crucial win in their bid to avoid the drop.
Tondela vs. Porto (Saturday, 6.00pm)
After a 2-0 defeat in the first leg of their Champions League quarter-final tie with Chelsea on Wednesday, Porto will look to bounce back with a fifth consecutive league win on Saturday, when they travel to take on Tondela.
With nine games left to play, Os Dragoes sit second in the Primeira Liga table, eight points behind league leaders Sporting Lisbon, while the hosts have moved up to ninth and away from the threat of relegation thanks to an upturn in form.
We say: Tondela 1-2 Porto
The hosts will certainly be no pushovers on Saturday, having put together a decent run of form, but we see Porto coming out with a narrow win with a full squad available to pick from.
With the battle for second spot hearing up, Conceicao's side need to ensure they keep winning, and they should have enough to pick up three crucial points on the road.
Pacos de Ferreira vs. Benfica (Saturday, 8.30pm)
An upturn in form has seen As Aguias move back up to third spot in the Primeira Liga table, while their hosts remain fifth despite an inconsistent run in recent weeks.
We say: Pacos de Ferreira 0-2 Benfica
As Aguias are building up a head of steam right now, and we see them picking up another fairly dominant victory on Saturday.
The attacking threat of the likes of Seferovic, Pizzi and Waldschmidt should have more than enough to break through the hosts' back line, while their strong defensive run could continue with a seventh consecutive clean sheet in all competitions.