AVS vs. Santa Clara (Saturday, 3.30pm)
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Santa Clara will be looking to secure consecutive league wins for the first time since the turn of the year when they visit the Estadio do Desportivo das Aves to face AVS on Saturday.
The home side, who currently sit one point above the bottom three, will be looking to snap their run of three back-to-back defeats against the Azoreans and pull clear of the danger zone.
We say: AVS 1-2 Santa Clara
Santa Clara picked up a hard-fought victory over Casa Pia last time out and will head into the weekend in high spirits as they continue their push for European football. AVS have struggled for consistency this season, and while we expect them to put up a fight, we are backing the visitors to come away with a narrow victory.
> Primeira Liga preview: AVS vs Santa Clara
Benfica vs. Moreirense (Saturday, 6.00pm)
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Second-placed Benfica could close the gap atop the Primeira Liga table in gameweek 21 when they host struggling Moreirense at Estadio da Luz on Saturday.
With third-placed Porto hosting table-topping Sporting Lisbon on Friday, the Eagles could reduce the six-point deficit after the forthcoming round if they claim maximum points against an opponent that have lost four of five away matches (one draw) before this weekend.
We say: Benfica 3-1 Moreirense
Benfica have conceded in four of their last five Liga fixtures and six of nine in all competitions in 2025, pointing to Moreirense finding the back of the net on Saturday.
However, Lage's side should ultimately overpower the out-of-sorts visitors to inflict the away side's fifth league loss in six on their travels.
> Primeira Liga preview: Benfica vs Moreirense
Famalicao vs. Guimaraes (Saturday, 8.30pm)
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Seeking to secure their first home win since August, Famalicao welcome Vitoria de Guimaraes to the Estadio Municipal de Famalicao in round 21 of the Primeira Liga on Saturday.
Having won each of the last three meetings between the teams, Os Vimaranenses will head into the weekend looking to extend their recent dominance over the hosts and pick up back-to-back victories for the first time since November.
We say: Famalicao 1-2 Vitoria de Guimaraes
Having both secured much-needed victories last time out, Famalicao and Vitoria de Guimaraes will be looking to get one over the other and put together a fine run of form. Os Vimaranenses boast a slightly superior and more experienced squad and we fancy them to secure a fourth straight win over the home side.
> Primeira Liga preview: Famalicao vs Guimaraes
Ben Knapton
