The Asian side have only earned one point so far in the tournament but will qualify for the last 16 if they beat Marc Wilmots's side by more goals than Russia, if they see off Algeria.
Hong Myung-Bo's side will also progress if they beat Belgium by three goals and Algeria and Russia share a draw.
Despite already guaranteeing a place in the last 16, Belgium are not sure to finish top of the group. If they are beaten and Algeria overcome Russia, then the African side will finish in first place.
Thomas Vermaelen is also struggling with injury and may have to sit out.
The last time these two sides met was in a friendly 15 years ago when Sandy Martens scored twice for Belgium in a 2-1 win.
South Korea: LDLLWL
Possible starting lineups
South Korea: Jung S-R, Yun S-Y, Kim Y-G, Son H-M, Park C-Y, Lee Y, Koo J-C, Han K-Y, Ki S-Y, Lee C-Y, Hong J-H
Belgium: Courtois; Alderweireld, Van Buyten, Kompany, Vertonghen; Witsel, Fellaini, De Bruyne; Mertens, Mirallas, Origi
Sports Mole says: 0-2