The hosts have drawn three of their opening five games at home, although they are tough to beat in front of their own fans with just one defeat.
Bayern are starting to find their scoring touch with 12 goals in their last three in all competitions, but they have been behind in each of their last two league games.
Possible starting lineups
Hoffenheim: Casteels; Beck, Abraham, Sule, Salihovic; Polanski, Rudy, Strobl, Firmino; Modeste, Volland
Bayern: Neuer; Rafinha, Van Buyten, Boateng, Alaba; Lahm; Robben, Schweinsteiger, Muller, Ribery; Mandzukic
Sports Mole says: 1-3