Araujo will be available again following a suspension, while Pique could recover from a groin problem to feature in the middle of the defence, as the latter's issue is not a serious one.
Sergino Dest and Clement Lenglet could drop out of the defence from Monday's 1-0 loss to Cadiz to allow Pique and Araujo to return, with the latter potentially operating at right-back against Real Sociedad.
Pedri is set to miss the remainder of the season with a hamstring problem, while Samuel Umtiti and Sergi Roberto are unlikely to be involved against the Basque outfit despite recently returning to training.
Ansu Fati is getting closer to a first-team return, and the Spain international has a chance of being in the squad for this match, with the attacker stepping up his injury recovery in training.
Barcelona possible starting lineup: Ter Stegen; Araujo, Pique, E Garcia, Alba; F de Jong, Busquets, Gavi; Dembele, Aubameyang, Torres