The Spanish champions have collected 25 points from their 12 league matches this season to top the pile, although they are level on points with second-placed Real Madrid.
Here, Sports Mole looks at how the Catalan giants could line up this weekend.
Valverde has a problem at right-back ahead of the match with Nelson Semedo out with a calf problem and Sergi Roberto unavailable due to a one-match suspension.
Ivan Rakitic is the only other injury doubt due to an Achilles issue, although the Croatia international is unlikely to start either way with Arthur, Sergio Busquets and Frenkie de Jong developing into the first-choice midfield.
Valverde has decisions to make further forward, though, when it comes to which two players join Lionel Messi in attack.
Ansu Fati and Antoine Griezmann both started against Celta before the international break, but Luis Suarez is expected to return to the XI for this game, meaning that Ousmane Dembele could be left out once again.body check tags ::