Vilanova replaced Pep Guardiola as the Blaugrana coach this summer and will be in charge of the team for the first time in a competitive match on Sunday.
Barcelona host Real Sociedad at Camp Nou in their opening game of the Primera Division campaign, and speaking ahead of the game on Saturday, Vilanova underlined his objectives for 2012-13.
"I'm hoping to win it all, that's what I'm hoping for this season," he said. "We have a good enough team to win any match. We'll have to think one match at a time.
"Barca are used to winning everything, especially in the last few years. We have to try and keep the ball, have the ambition to win and know who we are competing against.
"Last season we won four titles including the World Club Championship. We certainly did win, and a lot. And they (the players) look just as ambitious to me as always."
Defending Spanish champions Real Madrid welcome Valencia at the Santiago Bernabeu on Sunday.