The former Arsenal midfielder showed his frustration on the bench after being replaced in Valencia, but he has insisted that the reaction was not due to anger towards his manager.
"My reaction after I was substituted? I was frustrated with the game, not that I was taken off," he told reporters at a press conference.
"I felt good and we were creating chances. It was the frustration you get when the ball just doesn't want to go in.
"I have the sense that we could have played better in the first half, but in the second we dominated. We controlled the game, we were a bit unlucky."
Fabregas has scored seven times in the league this season.