Rayo Vallecano vs. Barcelona (Saturday, 1.00pm)
Xavi's side, who are third in the table, edged past Alaves before the international break, while 10th-placed Rayo Vallecano suffered a 2-1 home defeat to division leaders Girona last time out.
We say: Rayo Vallecano 1-2 Barcelona
Rayo's recent record against Barcelona will hand them confidence, and the visitors are not exactly in their best moment when it comes to performances and results. The Catalan giants often find a way to pick up wins when they need to, though, and we are backing them to secure an important three points this weekend.
Valencia vs. Celta Vigo (Saturday, 3.15pm)
Los Che suffered a 5-1 loss to Real Madrid at Bernabeu before the international break, while Celta were on the wrong end of a seven-goal thriller with Athletic Bilbao in their last game.
We say: Valencia 1-0 Celta Vigo
Celta are a difficult team to back at the moment, especially away from home, and we are struggling to predict a positive result for Benitez's side here. Valencia will be aiming to bounce back from their disappointing performance at Real Madrid, and the hosts should have enough quality to triumph.
Getafe vs. Almeria (Saturday, 5.30pm)
The visitors are rock bottom of the table, collecting only three points from their first 13 matches, while Getafe are in 11th position, picking up 16 points from their opening 13 games of the season.
We say: Getafe 1-0 Almeria
Getafe are not losing at the moment, but they are finding it difficult to win, and Almeria certainly have the quality to avoid defeat this weekend. We are expecting a very tight game in terms of the scoreline but believe that Getafe will be able to pick up all three points courtesy of a narrow success.
Atletico vs. Mallorca (Saturday, 8.00pm)
Diego Simeone's side, who are fourth in the table, beat Villarreal 3-1 in Spain's top flight before the international break, while 17th-placed Mallorca suffered a 2-0 loss to Real Betis in their last match.
We say: Atletico Madrid 2-0 Mallorca
Mallorca are capable of making this a tricky match, with the visitors drawing half of their league games this season. Atletico are so strong at home, though, and we are expecting them to record their 10th league victory of the campaign this weekend.