Granada vs. Atletico (Saturday, 1.00pm)
Atleti, who have still only lost one league game so far this season, will be looking to get back to winning ways after they were held to a 2-2 draw against Celta Vigo last time out.
We say: Granada 1-2 Atletico Madrid
Simeone's COVID-19 crisis has impacted performances in recent weeks and, if anything will trip Atleti up this weekend, it will be their lack of first-team regulars in the side. However, it is very unlikely that Atleti will fail to win twice in two league outings, so we are going with a 2-1 scoreline to the visitors.
Sevilla vs. Huesca (Saturday, 3.15pm)
Despite their lowly position in La Liga, Huesca have been enjoying their football of late and have put in a number of positive performances in recent weeks. However, beating Julen Lopetegui's high-flying Sevilla team might be a step too far for the Aragon side.
We say: Sevilla 2-0 Huesca
There is no question that Huesca have upped their game in recent weeks, but getting the better of Sevilla will likely be a step too far for Pacheta's men. Los Palanganas are in great form at the moment and a straightforward three points this weekend is definitely on the cards.
Eibar vs. Real Valladolid (Saturday, 5.30pm)
With both teams currently neck-and-neck at the foot of the La Liga table, this clash could go a long way in deciding who will be playing Segunda Division football next season.
We say: Eibar 2-2 Real Valladolid
This will be a very intriguing encounter between two sides that are just as bad as each other, and neutrals are likely to have a real dogfight on their hands. We cannot see anything separating the two sides but are expecting a few fireworks.
Barcelona vs. Alaves (Saturday, 8.00pm)
The Catalan outfit have work to do if they are to turn their Copa del Rey last-four tie around, but Ronald Koeman's side have recently been in impressive form in the league, winning each of their last six matches.
We say: Barcelona 2-0 Alaves
Barca will be determined to bounce back from the loss to Sevilla, and we are finding it difficult to back anything other than a home win. Alaves secured an impressive result against Valladolid last weekend, but we are expecting Koeman's side to pick up all three points to continue their strong run in La Liga.