The pair both failed to get on the scoresheet as Atletico were defeated by Barcelona at the weekend, but Simeone shows his intent to win this competition by starting both men at the Wanda Metropolitano.
The inclusion of Corluka is the only change from the side which began the goalless draw with Spartak Moscow at the weekend.
Atletico Madrid: Werner; Juanfran, Gimenez, Lucas, Luis; Thomas, Saul, Correa, Koke; Griezmann, Costa
Subs: Dos Santos, Vrsaljko, Montoro, Gabi, Vitolo, Torres, Gameiro
Lokomotiv Moscow: Guilherme; Ignatjev, Corluka, Kvirkvelia, Rybus; Miranchuk, Denisov, Pejcinovic, Fernandes; Miranchuk, Eder
Subs: Kochenkov, Barinov, Tarasov, Rotenberg, Lysov, Kolomeytsev, Myhkhalyk
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