Atleti ensured that they put at least one foot in the quarter-finals thanks to a 3-0 win in the Spanish capital, as goals from Saul Niguez, Diego Costa and Koke handed Simeone's men a comfortable win over the Russian side.
"In the whole match we were superior," Simeone told reporters after the game. "In the first half we did not play so well, had to answer some questions that they had posed.
"In the second half we stopped them better. With three in between we had more tranquility and the game was more continuous and fast.
"We will have to adapt in the best way so that this result has weight in the second leg."