Saul, who scored Atletico's goal against Barcelona, retains his place in midfield and Griezmann, who scored a penalty in Atletico's Champions League loss to Chelsea, is partnered with Kevin Gameiro up top.
Qarabag midfielder Pedro Henrique, who scored his side's only goal in their 2-1 loss to Roma in their previous Champions League tie, keeps his place in midfield.
Qarabag FK: Sehic; Medvedev, Sadygov, Guseynov, Agolli; Madatov, Garayev, Almeida, Henrique; Michel, Ndlovu
Atletico Madrid: Oblak; Luis, Godin, Gimenez, Vrsaljko; Gabi, Saul, Gaitan; Griezmann, Carrasco, Gamiero
Subs: Moya, Savic, Lucas, Thomas, Augusto, Torres, Correa
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