The Partenopei have drawn their past two league games, which has seen seem slip 12 points behind leaders Juventus.
They are just three points clear of Fiorentina and will want to maintain their target of finishing in the Champions League qualifying spots.
Despite their recent stutter, they are unbeaten in 10 games, and booked their place in the semi-finals of the Coppa Italia after claiming a 1-0 win against Lazio in midweek.
Their opponents Atalanta are 12th in the table, and after two successive league victories, they slipped to a 1-0 defeat last weekend against Torino.
The two teams have met each other twice this season, in both Serie A and the Coppa Italia, with Napoli running out winners on both occasions.
Possible starting lineups
Atalanta: Consigli, Benalouane, Stendardo, Yepes, Grosso, Raimondi, Migliaccio, Cigarini, Bonaventura, Moralez, Denis
Napoli: Reina, Maggio, Albiol, Fernandez, Reveillere, Inler, Frello, Mertens, Hamsik, Callejon, Higuain
Sports Mole says: 0-2