Paul Lambert's side will be keen to put a difficult week in cup competitions behind them, having been knocked out of the League Cup and FA Cup by lower-league opposition in the space of four days.
Villa should have no fresh injury concerns from Friday night's loss to Millwall, but it seems likely that there will be a different look to the side to face Newcastle.
The Magpies have no fresh injury concerns from their loss to Reading last weekend, having already been knocked out of both cup tournaments.
The team are 18th and 19th respectively in the Premier League form table, with just one win between them in their last 12 games.
Aston Villa: LLLDLD
Newcastle United: WLLLDL
Possible starting lineups
Aston Villa: Guzan, Vlaar, Clark, Bennett, Baker, Lowton, Westwood, Delph, N'Zogbia, Bent, Benteke
Newcastle United: Krul, Debuchy, Williamson, Coloccini, Santon, Anita, Cabaye, Shola Ameobi, Sissoko, Gutierrez, Cisse
Sports Mole says: 0-1