The former is nearing a return to action from a thigh issue but will not be risked with the FA Cup final in mind, while Christensen was taken off just before half time against Manchester City with an issue in the same area.
Billy Gilmour played the full 90 minutes against Man City but might make way for the returning Jorginho, while Ben Chilwell should earn a recall to the left after being rested entirely at the weekend, meaning that match-winner Marcos Alonso could drop out.
Reece James should be fit enough to continue on the opposite side, while Hakim Ziyech will hope that his goal at the Etihad Stadium has seen him do enough to warrant another start in quick succession.
Mason Mount was nowhere to be seen against Man City so will certainly return here - most likely over Christian Pulisic - while the returning Kai Havertz could displace Timo Werner at the forefront of the attack.
Chelsea possible starting lineup: Mendy; Azpilicueta, Zouma, Rudiger; James, Jorginho, Kante, Chilwell; Ziyech, Mount; Havertz
Watch the Sports Mole Football Shorts prediction for this game below: