Thibaut Courtois, who has been strongly linked with a move to Real Madrid, remains unavailable following the 2018 World Cup, while the likes of Eden Hazard and Willian are still absent for the London outfit.
Aaron Ramsey also starts despite the speculation surrounding the Welshman's future.
Chelsea: Caballero; Azpilicueta, Luiz, Rudiger, Alonso; Jorginho, Fabregas, Barkley; Pedro, Morata, Hudson-Odoi
Subs: Bulka, Green, Zappacosta, Ampoadu, Christensen, Emerson, Moses, Drinkwater, Loftus-Cheek, Bakayoko, Piazon, Abraham
Arsenal: Cech; Bellerin, Mustafi, Sokratis, Kolasinac; Elneny, Ramsey, Guendouzi; Mkhitaryan, Aubameyang, Ozil
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