Both clubs came through their third-round matches in the Capital One Cup this week and Arsenal in particular will be hoping to continue their league form following their 1-1 draw with Manchester City at the weekend.
Chelsea remain on top of the league table and will be hoping to stay there when they travel to the Emirates on Saturday.
Arsene Wenger has revealed today that defender Thomas Vermaelen should be fit to play this weekend, while midfielder Jack Wilshere is slowly on the road to first-team action after the Frenchman confirmed that the England international will compete in a reserve match on Monday.
Meanwhile, Roberto Di Matteo could start captain John Terry depending on the outcome of an FA hearing, which is due to rule today whether the centre-back racially abused Queens Park Rangers defender Anton Ferdinand almost a year ago.
Arsenal: Mannone; Jenkinson, Koscielny, Vermaelen, Gibbs; Ramsey, Diaby, Arteta, Cazorla; Giroud, Podolski
Chelsea: Cech; Ivanovic, Luiz, Terry, Cole; Mikel, Oscar; Ramires, Mata, Hazard; Torres
Sports Mole says: 1-1