Cazorla and Ozil are among a number of creative attacking midfield players at Wenger's disposal this season, but the duo have only started one match together so far due to an injury to the Spaniard.
A number of pundits have raised questions over how the two players will co-exist due to their similar styles of play, but Wenger believes that the more creativity there is in a side, the better it will be.
"The more you have the better is it. They can play together. I did not start Cazorla [against Dortmund] on Tuesday night because I did not feel he was completely ready physically, but when he came on he did well," Wenger told PA.
"Ozil said he was alright, but in the two days before he had a virus and you could see that physically he was not at his best. Dortmund, though, were organised to stop us from playing our game and one of their game plans was to stop Ozil from getting into the game and they did that."