After a dominant 3-1 win over Bolivia in their opening game of the group stage, Paraguay manager Eduardo Berizzo is expected to stick with an unchanged side for Tuesday's Copa America clash with Argentina.
Winger Angel Romero will feature in the front line, after he hit a brace in that game to seal all three points.
Alejandro Romero scored the equaliser in that encounter, and he will also play a key role in an exciting attacking line.
Rounding off the three behind the striker is Newcastle United attacker Miguel Almiron, who has the ability to cause Argentina major concerns with his pace and dribbling ability.
After a solid performance in the opening game, the back four of Alberto Espinola, Gustavo Gomez, Junior Alonso and Santiago Arzamendia should remain unchanged, as they look to neutralise one of the world's standout front lines.
Mathias Villasanti will also sit in front of the defensive line, with the Cerro Porteno star putting in an impressive display in their opening win.
Berizzo may look to find a spot for talented midfielder Oscar Romero, but given the quality of Argentina's attacking line, he may instead opt to go with more defensive cover in his midfield unit in the form of Robert Piris Da Motta.
Paraguay possible starting lineup: Silva; Espinola, Gomez, Alonso, Arzamendia; Piris, Villasanti; Alejandro Romero, Almiron, Angel Romero; Avalos