AC Milan vs. Salernitana (Saturday, 2.00pm)
Successive defeats had provided a first serious setback for the second-placed Rossoneri before they swept aside Genoa on Wednesday, while their southern counterparts fell to an 11th league defeat of the campaign.
We say: AC Milan 3-0 Salernitana
A rejuvenated Milan were far livelier in midweek, so the opportunity to welcome struggling Salernitana to San Siro presents them with another chance to secure three points to keep their Scudetto challenge ticking over.
Goals have been in particularly short supply for the southern side, so the hosts can flood forward without fear of conceding.
Roma vs. Inter Milan (Saturday, 5.00pm)
A third league loss in their last five leaves the Giallorossi trailing in the champions' wake after they were defeated at Bologna, while Inter strode to a fifth win from six in the Italian top flight.
We say: Roma 1-2 Inter Milan
Inter's greatest foes Milan last punctured Roma's excellent home record in Serie A, and the impressive Nerazzurri can make it a double triumph for the second city on Saturday.
Inzaghi has certainly put his own stamp on things in the champions' dugout, and the deeper, more harmonious squad at his disposal will help him overcome Mourinho's men in a tightly-fought capital skirmish.
Napoli vs. Atalanta (Saturday, 7.45pm)
In a fixture which has been reliably entertaining in recent times, the Scudetto hopefuls convene in Campania with the hosts now just five points clear of their visitors following a late collapse at Sassuolo in midweek.
We say: Napoli 2-2 Atalanta BC
While both sides possess the firepower to blow away all-comers when in top gear, something must give when two of the Serie A's great entertainers meet in Naples.
Undoubtedly, form is in Atalanta's favour ahead of the match, but Napoli's proud record at Stadio Maradona this year can help the league leaders overcome some significant absences through the spine of their team.