Villas-Boas said that conceding at home against Lyon in the last round made qualification difficult and wants to avoid the same scenario this time around.
"We don't want to concede a goal," he told the club's official website. "We were unlucky to concede against Lyon at home but it was a goal that put questions into the second leg.
"We want avoid that happening, so we need to be consistent and try to be as good as we have been recently in attack to take an advantage into the second leg.
"Inter are very smart, very experienced and nothing will be decided in this first leg, for sure."