The Premier League champions have slumped 13 points below leaders Arsenal in the league table following defeats to Everton and Newcastle United.
"It's very important we get back to winning at Old Trafford," Rafael told MUTV. "It's our home and we have to play well here for our supporters. We should do this on Tuesday.
"Of course, everyone is disappointed with the results [against Everton and Newcastle] and the way we played. Now we must bounce back and try to get the wins again."
United are currently unbeaten in their European campaign.