The 2008 world champion has won three races in a row with Mercedes, but has never won in F1 at the Circuit de Catalunya, finishing on the podium three times.
The Briton told Sky Sports News: "It's been good to have a bit of a break between races, for us as drivers and also for the team who have been working flat out for so many weeks.
"Barcelona is a great place to have the first European round on the calendar. It's a circuit we all know very well, although this is the first time in my Formula 1 career that I have raced there without testing at the circuit during the winter, and the Spanish crowds are really passionate about their racing.
"It's great to see so many people in the grandstands over the weekend. I've never won in Barcelona but I'm in a good place right now and I'm hoping that this will be the year, although it's clear who the fans' favourite will be! The circuit is fantastic, our car has performed well so far and I'm really looking forward to a good race."