West Ham and Brighton have each taken one point from their last three Premier League matches and either side could find themselves in the drop zone if they lose on Saturday and results elsewhere go against them.
While fixtures against Sheffield United, Everton, Leicester City and Liverpool are by no means easy, the former Manchester United boss will have hoped for a better return.
The Hammers have struggled at home all season and have the league's joint-worst record on their own patch, taking just 11 points from 12 matches at the London Stadium.
The meeting between these two sides at the Amex Stadium in August ended 1-1, a result that would not please either manager this time around.
Brighton made a good start to life under Graham Potter but have struggled in recent weeks, with the Seagulls taking just five points from their last six matches.
A defeat to fellow strugglers Bournemouth last time out will have been particularly disappointing for Potter, whose side have found it tough away from home all season.
The South coast club have the second-worst record in the league on the road, winning just twice.
However, Brighton have also faced a difficult run of fixtures of late and can make up for lost ground with a win over West Ham on Saturday.
West Ham United Premier League form: LWLDLL
West Ham United form (all competitions): WLDLLL
Brighton & Hove Albion Premier League form: LWDLDL
Brighton & Hove Albion form (all competitions): WDLLDL
West Ham are assessing Michail Antonio after the winger missed out against Liverpool with a thigh injury, in the hope that he could be fit enough to face Brighton.
Brighton centre-back Shane Duffy is hoping to return after he sat on the bench because of a calf injury during the Seagulls' loss to Bournemouth in their last Premier League fixture.
Jose Izquierdo could also return from a knee injury that has stopped him featuring at all this season.
West Ham United possible starting lineup:
Randolph; Zabaleta, Ogbonna, Diop, Cresswell; Noble, Rice, Fornals; Snodgrass, Haller, Lanzini
Brighton & Hove Albion possible starting lineup:
Ryan; Alzate, Webster, Dunk, Bernardo; Propper, Mooy, Stephens; Trossard, Maupay, Connolly
We say: West Ham United 1-2 Brighton & Hove Albion
In a battle between one of the worst home sides in the Premier League and one of the worst away sides, a draw seems inevitable. However, Brighton have looked the better team this season and if they play their best, they can earn a valuable win on Saturday.