Newcastle vs. West Ham (Saturday, 12.30pm)
The Hammers are currently fourth in England's top flight, one point behind third-placed Leicester City, while Newcastle occupy 17th position, now six points clear of the relegation zone.
We say: Newcastle United 1-2 West Ham United
Newcastle are still under pressure towards the bottom of the table, but the Magpies are not in any immediate danger of dropping into the relegation zone, which could work in West Ham's favour. The Hammers will again be missing some key players on Saturday, but we fancy them to just have enough to edge out another victory to move into third position in the Premier League table.
Wolves vs. Sheff Utd (Saturday, 8.15pm)
The Blades are 18 points adrift and it will be mathematically impossible for them to escape the drop should they lose at Molineux and Newcastle United beat West Ham United.
We say: Wolverhampton Wanderers 2-0 Sheffield United
Wolves beat United 2-0 in September's reverse match and are seeking their first league double in this fixture since the 2013-14 League One campaign.
Nuno's men have been incredibly inconsistent this term, but we can see them picking up rare back-to-back wins against a side whose relegation fate could be sealed this weekend.