Carvalhal had a near-full strength squad at his disposal for the match in Wales, with only Kyle Bartley missing through injury.
With both sides heading into the match level on 33 points, in 17th and 18th in the division, defeat for either would leave them in deep relegation trouble going into the final weekend, while anything other than a draw will relegate West Bromwich Albion.
Swansea City: Fabianski; Naughton, Fernandez, Mawson; Roberts, Ki, King, Olsson; Clucas, A Ayew, J Ayew
Subs: Nordfeldt, Van der Hoorn, Carroll, Sanches, Dyer, Narsingh, Abraham
Southampton: McCarthy; Bednarek, Stephens, Hoedt; Soares, Romeu, Hojbjerg, Bertrand; Tadic, Redmond, Austin
Subs: Forster, McQueen, Ward-Prowse, Sims, Long, Carrillo, Gabbiadini
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