The visitors, meanwhile, sit bottom of the pile in League One after losing nine of their last 10 matches.
Sunderland enter Saturday's contest in fifth position, but with two points separating them from seventh-placed Wycombe Wanderers, Alex Neil will be fully aware that his side can not afford a drop in form.
The Black Cats have impressed in recent encounters after picking up eight points from their last four matches, and they will be aiming for consecutive victories on Saturday following their 3-1 home win over Fleetwood Town in midweek.
Neil's side trailed at half time after Ellis Harrison opened the scoring, but Sunderland demonstrated their quality in the second period to claim all three points thanks to goals from Elliot Embleton, Luke O'Nien and Jack Clarke.
Despite their promising run of form, Sunderland have experienced mixed results on home turf in recent matches, with their last six home games yielding three defeats, two victories and a draw.
However, they still boast the third-best home record in League One this term after collecting 38 points from their 18 league matches at the Stadium of Light, and that home form will be crucial in their quest to finish in the playoffs.
At the other end of the table, Crewe's two-season stay in League One looks to be drawing to a close with the Railwaymen sitting rock bottom of the league table.
Eight points adrift of safety with only 10 matches left to play, David Artell's side require a great escape if they are to beat the drop this season.
Recent results suggest that such a feat is unlikely, with Crewe collecting the lowest points tally of any side in League One in 2022.
Only Doncaster Rovers (72) and Morecambe (67) have conceded more goals than the Railwaymen (66) this term, and their defensive fragility was on full display in midweek when they suffered a 3-1 defeat at home to Portsmouth.
After playing consecutive home games, Crewe will now take to the road, and they will be looking to draw inspiration from the 2-1 victory that they picked up against Cheltenham Town in their most recent away trip.
Neil has utilised different formations since taking over as Sunderland boss, including a half-time switch to a back three in Tuesday's win over Fleetwood, and he is expected to opt for three centre-backs once again on Saturday.
O'Nien may have earned himself a starting berth after scoring in his 20-minute appearance in the midweek win over Fleetwood.
Ross Stewart will once again lead the line as the current League One top scorer looks to add to his 22-goal tally.
Rekeem Harper could be in contention for a starting place after being introduced in the second half against Portsmouth.
Sunderland possible starting lineup:
Patterson; Winchester, Wright, Xhemajli; Gooch, Matete, O'Nien, Cirkin; Embleton, Clarke, Stewart
Crewe Alexandra possible starting lineup:
Richards; Johnson, O'Riordan, Offord; Agyei, Murphy, Harper, Lowery, Lundstram; Porter, Long
We say: Sunderland 3-0 Crewe Alexandra
With Sunderland unbeaten in their last four matches, we think that the hosts will make light work of a Crewe side, who are bereft of confidence after losing nine of their previous 10 games.