Hughes's side are currently 16th with just two wins, but the manager said that he does not think they are too far away from finding the right combination.
"We've made opportunities, but we haven't been taking them," the club's official Twitter feed quotes him as saying. "We do feel that we will start to convert them sooner, rather than later.
"We have a lot of different options up top. We need to find that one combination which will be able to carry us through the season."
"We need to get the right balance and the right combination. I think we are close to finding the right one."
Stoke take on Manchester United at Old Trafford on Saturday.