The Dutchman will provide support for Jermain Defoe in attack for Spurs while Younes Kaboul is replaced in central defence by Jan Vertonghen.
Emmanuel Adebayor is on the bench following his permanent switch to White Hart Lane and Gylfi Sigurdsson is also named as a substitute.
West Brom are looking to build on their 3-0 victory over Liverpool last week and Shane Long will once again lead the line for the Baggies. Romelu Lukaku is on the bench despite his impressive goal in the win.
Tottenham: Friedel, Walker, Vertonghen, Gallas, Assou-Ekotto, Sandro, Livermore, Lennon, Bale, Van der Vaart, Defoe
West Brom: Foster, Reid, McAuley, Olsson, Ridgewell, Mulumbu, Yacob, Morrison, Fortune, Long, Dorrans