The recent arrival from Benfica is named among the away side's substitutes, but Giovani Lo Celso and Erik Lamela are both in the side following their impressive displays against Middlesbrough in the FA Cup.
Christian Eriksen, though, is again on the bench amid the speculation surrounding his future.
Christian Kabasele is available once again following suspension but is named on the bench.
WATFORD: Foster; Mariappa, Dawson, Cathcart, Masina; Capoue, Chalobah; Sarr, Doukoure, Deulofeu; Deeney
TOTTENHAM HOTSPUR: Gazzaniga; Aurier, Alderweireld, Vertonghen, Tanganga; Winks, Lo Celso, Alli; Lamela, Lucas, Sonbody check tags ::