Villa are unbeaten in their last three matches, winning two in succession before their stalemate at Hull City a fortnight ago.
Spurs ran out 4-0 winners at Villa Park when the two sides met in the third round of the League Cup last month.
Villa boss Paul Lambert could name Christian Benteke in his starting XI after the striker was named on the bench for Belgium's World Cup qualifier against Wales on Tuesday night, following his recovery from a hip injury.
Aston Villa: LLLWDD
Possible starting lineups
Aston Villa: Guzan; Bacuna, Vlaar, Baker, Clark; El Ahmadi, Luna, Delph; Weimann, Agbonlahor, Benteke
Spurs: Lloris; Walker, Dawson, Vertonghen, Naughton; Dembele, Paulinho; Townsend, Eriksen, Sigurdsson; Soldado
Sports Mole says: 1-2